Gene therapy in oral cancer: A review

Author:

Johny Joseph1,Sreedhar Sinitha2,Nair Rohini S,Megha I J Liz,Sankar V B Vidya

Affiliation:

1. Sree Anjaneya Institute of Dental Sciences, Calicut, Kerala, India

2. S

Abstract

Gene therapy is the utilization of DNA as a specialist to treat illness. Gene therapy focuses on the inclusion of a functional gene into the cells of a patient for the rectification of an inborn error of metabolism, to change or fix a procured hereditary irregularity, and to give new capacity to the cell. Today, vast majority of the gene therapy studies are focused on malignant growth and inherited diseases which are connected to hereditary deformities. Malignant growth typically happens because of the creation of various mutations in a solitary cell which makes it proliferate wildly. A few techniques like surgery, radiation treatment, and chemotherapy have been utilized generally to treat tumors, yet recurrence is normal in roughly 33% of patients. To further develop the therapy methodology and to expand the endurance rate, gene therapy can be utilized as an aid to different treatments for malignant growth in patients. The reason for this article is to audit the ideas and strategy, with a knowledge into the ebb and flow research on its applications in oral squamous cell carcinoma (OSCC).

Publisher

IP Innovative Publication Pvt Ltd

Reference21 articles.

1. Sunil PM, Ramachandran CR, Devy S, Varghese SS, Cytogenetic alterations in oral squamous cell carcinoma detected by karyotyping (g-banding).Oral Maxillofac Pathol J 2011;2(1):89-95

2. Current concepts in oral cancer

3. Sunil P M, Isaac Joseph, Varghese Soma Susan. Gene therapy in oral squamous cell carcinoma - a short review.Oral and Maxillofacial PatholJ 2011;2(2):142-7

4. Mohan SP, Ramachandran CR, Jaisanghar N, Kumar CS, , Dental Surgeons as Gene Therapist.Int J Oral Maxillofacial Pathol 2012;3(3):65-7

5. Singh A, Badni M, Singh A, FM Samadi, Kabiraj A, Gene therapy for oral cancer - journey to a new horizon.Oral Maxillofacial Pathol J 2012;3(1):203-10

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3