Study of histomorphological spectrum of malignant breast diseases- In a tertiary care centre of Mumbai

Abstract

Breast cancer is the most common cancer in women worldwide, comprising 16% of all -female cancers. It is by far the most frequent cancer in female, both in developed and developing regions and is second overall next only lung. In India, breast cancer is the most common cancer among women in many regions and has overtaken cervix cancer, which was the most frequent cancer a decade ago 5 As in other developing regions, the mortality rates for breast cancer in India are high in comparison to its incidence rates. A poor survival may be largely explained by the lack of or limited access to the early detection services and treatment. Though clinical examination of the breast lump and the age of the patient can provide information about the nature of the lump, Histopathological examination is necessary to establish the diagnosis. To classify the breast lesions and study them with age, clinical presentation and various pathological parameters. The present study of the breast lesions was performed in the department of pathology in a general teaching hospital and tertiary referral health care centre in Mumbai. All the assimilated data was collected and analysed to find the incidence and frequency of lesions. Infiltrating duct carcinoma (IDC) is the most common breast malignancy. Grade -2 IDC’s were more common than grade- 1 and grade-3 IDC’s. Breast cancers were bulky and presented at an advanced stage in younger population. Breast carcinomas in our population presents as locally advanced cancer, with predominance of higher histological grade and higher stage in view of lack of or limited access to the early detection services and treatment.