Affiliation:
1. Jawaharlal Nehru Medical College and Hospital, Aligarh, Uttar Pradesh, India
2. J
Abstract
Papillary carcinoma is the most common malignancy of thyroid accounting for about 80-90% of thyroid cancers. The most common site of metastasis is lung and bone. Distant metastasis is associated with poor prognosis in thyroid cancers in terms of decreased survival rates. Metastasis to mandible is a rare occurrence in thyroid cancers and very few cases have been reported in literature. Here we present a case of 45-year-old female who presented with complaints of pain and swelling in right side of mandible for past 10 months. On examination, a 3x3 cm hard, non-mobile growth on right side of mandible was seen. Microscopy revealed features of metastasis from papillary thyroid carcinoma, which were later confirmed by immunohistochemistry. Mandibular metastasis of thyroid cancer is exceedingly rare, however in cases presenting initially with jaw swelling it must be kept as a differential diagnosis.
Publisher
IP Innovative Publication Pvt Ltd
Reference9 articles.
1. Germain MA, Marandas P, Leridant AM, Domenge C, Julieron M, Schlumberger M, Isolated mandibular metastasis of cancer of the thyroid. Mandibulectomy and reconstruction using a free vascularised peroneal graft.Rev Stomatol Chir Maxillofac 1998;98(6):371-4
2. Nikitakis NG, Polymeri A, Polymeris A, Sklavounou A, Metastatic papillary thyroid carcinoma to the maxilla: case report and literature review.Head Neck Pathol 2012;6(2):216-23
3. Pittas AG, Adler M, Fazzari M, Tickoo S, Rosai J, Larson SM, Bone metastases from thyroid carcinoma: clinical characteristics and prognostic variables in one hundred forty-six patients.Thyroid 2000;10(3):261-8
4. Fatahzadeh M, Subramanian G, Singer SR, Metstatic papillary thyroid carcinoma to maxilla: A rare case.Quintessence Int 2015;46(5):431-5
5. Irani S, Metastasis to the jawbones: a review of 453 cases.J Int Soc Prev Community Dent 2017;7(2):71-81