Comparative study between conventional and field-infield techniques in early-stage breast cancer radiotherapy

Abstract

“Breast cancer is one of the foremost reasons for cancer death in the fewer developed countries of the world. This is partially because a change in lifestyles it’s affecting growth in occurrence and partially because of clinical advances to combat the disease are not reaching women existing in these regions. Adjuvant radiotherapy given subsequent operation for primary carcinoma of the breast has been revealed to reduce the occurrence of locoregional reappearance from 30% to 10.5% at 20 years and breast cancer deaths by 5.4% at 20 years. 40 patients by initial-stage breast cancer underwent calculated tomography. 2 diverse treatment strategies were created for each patient: the wedge-based (conventional) strategy and the FIF plan. Dosimetric parameters and monitor components were associated with paired sample t-test. FIF technique gained significantly lower dose homogeneity index, lower maximum doses, and higher median doses in PTV (P<0.05). Similarly, the conformity index, and mean doses were higher in the FIF technique but the changes were not significant (P>0.05). In ipsilateral lungs, FIF significantly reduced the maximum and mean doses (P<0.05), and showed a tendency to reduce V20 (P>0.05). In patients with left-sided breast cancer, minimum and maximum doses and V40 of heart were significantly decreased in FIF plans (P<0.05). Doses to the contralateral lungs did not differ significantly. These results along with significantly fewer monitor unit’s essential for therapy in FIF suggest that this technique may be more advantageous during breast irradiation.