Siddha makardwaja and bhumiamalaki (Phyllanthus niruri) can reverse the progression of Non Alcoholic Steato-hepatitis(NASH): Case study

Abstract

A 45-year male, a business man came to our general OPD with elevated liver enzyme with elevated fasting blood glucose report in his hand. The patient was further advised for fibro scan and his Liver stiffness measurement (LSM) was 11kPa with CAP score 264dB/m with negative virus panel. The patient was diagnosed as Non-Alcoholic Steato-hepatitis (NASH) based on his overweight and biochemical and radiological findings 3000mg (Phyllanthus niruri) aqueous extract tablet (500mg) in two divided dose after food with luke warm water along with one tablet special Rasa 125mg twice daily before food triturate with honey for 10 minutes for six months. The symptom of dyspepsia and constipation were relieved in 1 month of treatment whereas mild change in liver fibrosis (LCM &CAP score) was observed in 1 three month of therapy and marked regression in liver stiffness was observed in after six months of therapy. The patient has no relapse of the liver fibrosis even after three years of observation. The patient had no adverse sign or symptom during medication and observed period. Rasa and (Phyllanthus niruri) combination therapy can reverse the Progression of Non-Alcoholic Steato-hepatitis (NASH) in six months of therapy and sustain the amelioration liver tissue even after discontinuation of medication in long term follow up.