Comparative study of obstetric outcome in women with one previous spontaneous miscarriage versus women with one previous normal delivery

Abstract

Spontaneous abortion is unintentional pregnancy loss before 20 weeks of gestation. This study was done to find out the association between one spontaneous pregnancy loss and adverse pregnancy outcomes in the subsequent pregnancy and to compare these pregnancy outcomes in patients with prior one full term normal delivery.: It is a case control study. 70 G2A1 were taken as cases, 70 G2P1L1 were considered as Control. The adverse pregnancy outcomes like preterm labour, PROM, IUGR and oligohydramnios and neonatal outcomes like poor Apgar score, low birth weight, NICU admissions and neonatal complications were noted compared and analysed between the two groups. Chi-square was used to find association between clinical variables. Independent t-test was used to compare the outcome measures between the groups.: Comparing the pregnancy outcomes of the case and control groups case group had a higher number adverse pregnancy or neonatal outcome, compared to the control group (p value = 0.05), adverse outcome were higher in case population, adverse outcomes which were independently associated with initial spontaneous abortion were oligohydramnios (p = 0.02), GDM (p = 0.05), LSCS (p = 0.01), low birth weight (p = 0.03), low Apgar scores 1 minute (p = 0.009), low Apgar score at 5 minute (p = 0.03) and babies requiring NICU care (p = 0.001).: Study shows that there is increase in adverse obstetric and perinatal outcomes in pregnancies which are following a single spontaneous abortion. Hence a prior spontaneous miscarriage is a risk factor for the adverse outcome in subsequent pregnancy, therefore careful prenatal care in such pregnancies are mandatory to avoid adverse pregnancy outcomes.