Successful outcome of pregnancy with aplastic anaemia: A case report

Abstract

Pregnancy in aplastic anaemia is rare and it may exacerbate bone marrow depression and cause deterioration, which can be life threatening for both mother and child. It poses a great challengeto the haematologist as well as obstetrician as the management of such cases challenges their skills in deciding the best treatment option for the patient. The first report of Aplastic anemia in Pregnancy was publised by Ehrlich in 1888. Haemorrhage and sepsis due to pancytopenia are the mainfactors responsible formortality in pregnant women with aplastic anemia. Treatment options are erythrocytes and platelet transfusions and immuno suppressive therapy. Immunosuppressive agents or hemopoietic stem cell transplantation are contraindicated during pregnancy. There is no universal agreement about the optimal treatment regime for this disorder in pregnancy, and supportive therapy remains the mainstay of therapy. The present case report describes our experience with a patient with aplastic anaemia, who was managed with intensive haematological support leading to delivery of a healthy baby.