Improving Workflow Integration with xPath: Design and Evaluation of a Human-AI Diagnosis System in Pathology

Author:

Gu Hongyan1ORCID,Liang Yuan1ORCID,Xu Yifan1ORCID,Williams Christopher Kazu2ORCID,Magaki Shino2ORCID,Khanlou Negar2ORCID,Vinters Harry2ORCID,Chen Zesheng2ORCID,Ni Shuo3ORCID,Yang Chunxu4ORCID,Yan Wenzhong1ORCID,Zhang Xinhai Robert5ORCID,Li Yang6ORCID,Haeri Mohammad7ORCID,Chen Xiang ‘Anthony’1ORCID

Affiliation:

1. University of California, Los Angeles, Los Angeles, CA

2. UCLA David Geffen School of Medicine, Los Angeles, CA

3. University of California, Los Angeles and University of Southern California, Los Angeles, CA

4. University of California, Los Angeles and Peking University, Los Angeles, CA

5. University of Texas Health Science Center at Houston, Houston, TX

6. Google Research, Mountain View, CA

7. University of Kansas Medical Center, Kansas City, KS

Abstract

Recent developments in AI have provided assisting tools to support pathologists’ diagnoses. However, it remains challenging to incorporate such tools into pathologists’ practice; one main concern is AI’s insufficient workflow integration with medical decisions. We observed pathologists’ examination and discovered that the main hindering factor to integrate AI is its incompatibility with pathologists’ workflow. To bridge the gap between pathologists and AI, we developed a human-AI collaborative diagnosis tool— xPath  —that shares a similar examination process to that of pathologists, which can improve AI’s integration into their routine examination. The viability of xPath  is confirmed by a technical evaluation and work sessions with 12 medical professionals in pathology. This work identifies and addresses the challenge of incorporating AI models into pathology, which can offer first-hand knowledge about how HCI researchers can work with medical professionals side-by-side to bring technological advances to medical tasks towards practical applications.

Funder

National Science Foundation

Publisher

Association for Computing Machinery (ACM)

Subject

Human-Computer Interaction

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