Multimodal Brain Tumor Segmentation Based on an Intelligent UNET-LSTM Algorithm in Smart Hospitals

Author:

Hu He-Xuan1,Mao Wen-Jie2,Lin Zhen-Zhou3,Hu Qiang2,Zhang Ye2ORCID

Affiliation:

1. Hohai University, and Tibet Agriculture & Animal Husbandry University, People's Republic of China

2. Hohai University, People's Republic of China

3. Nanjing University of Finance and Economics, People's Republic of China

Abstract

Smart hospitals are important components of smart cities. An intelligent medical system for brain tumor segmentation is required to construct smart hospitals. To achieve intelligent brain tumor segmentation, morphological variety and serious category imbalance must be managed effectively. Conventional deep neural networks have difficulty in predicting high-accuracy segmentation images due to these issues. To solve these problems, we propose using multimodal brain tumor images combined with the UNET and LSTM models to construct a new network structure with a mixed loss function to solve sample imbalance and describe an intelligent segmentation process to identify brain tumors. To verify the practicability of this algorithm, we used the open source Brain Tumor Segmentation Challenge dataset to train and verify the proposed network. We obtained DSCs of 0.91, 0.82, and 0.80; sensitivities of 0.93, 0.85, and 0.82; and specificities of 0.99, 0.99, and 0.98 in three tumor regions, including the whole tumor ( WT ), tumor core ( TC ), and enhanced tumor ( ET ). We also compared the results of the proposed network with those of other brain tumor segmentation methods, and the results showed that the proposed algorithm could segment different tumor lesions more accurately, highlighting its potential application value in the clinical diagnosis of brain tumors.

Funder

National Key R&D Program of China

National Natural Science Foundation of China

Key Research Projects of Tibet Autonomous Region for Innovation and Entrepreneur

Publisher

Association for Computing Machinery (ACM)

Subject

Computer Networks and Communications

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