Affiliation:
1. HARRAN ÜNİVERSİTESİ, SAĞLIK HİZMETLERİ MESLEK YÜKSEKOKULU
2. KAHRAMANMARAS SUTCU IMAM UNIVERSITY, KAHRAMANMARAŞ HEALTH ACADEMY
Abstract
Aim: This study was carried out to determine the activities of antioxidant enzymes in erythrocyte metabolism in healthy
individuals residing in Kahramanmaraş region according to their age.
Material and Methods: In order to detect the absence or insufficiency of Glucose-6-phosphate Dehydrogenase (G6PD),
Superoxide Dismutase (SOD) and Catalase (CAT) enzymes involved in erythrocyte metabolism, 281 healthy individuals
between the ages of 0-125 were included in the study. Hematological data of the individuals included in the study group
were normal.
Results: G6PD and CAT activities were determined by Beutler Method and SOD activity was determined by Fridovich
Method. G6PD enzyme deficiency (zero activity) was found in three individuals and catalase enzyme deficiency was found
in seven individuals.
Conclusion: In this study; G6PD and CAT activities increased with aging, while SOD activity decreased (p<0.05) and
enzyme activities did not differ depending on gender in the same age groups (p>0.05). As a result, it was concluded
that there is a positive correlation between aging and oxidative stress.
Publisher
Turkish Journal of Clinics and Laboratory
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