Insights Into the Activation and Inhibition of Angiotensin II Type 1 Receptor in the Mechanically Loaded Heart

Author:

Wu Jian1,You Jieyun1,Wang Shijun1,Zhang Li1,Gong Hui1,Zou Yunzeng1

Affiliation:

1. Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University

Publisher

Japanese Circulation Society

Subject

Cardiology and Cardiovascular Medicine,General Medicine

Reference60 articles.

1.  1. Zou Y, Akazawa H, Qin Y, Sano M, Takano H, Minamino T, et al. Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nat Cell Biol 2004; 6: 499–506.

2.  2. Zablocki D, Sadoshima J. Solving the cardiac hypertrophy riddle: The angiotensin II-mechanical stress connection. Circ Res 2013; 113: 1192–1195.

3.  3. de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T. International union of pharmacology. XXIII: The angiotensin II receptors. Pharmacol Rev 2000; 52: 415–472.

4.  4. van de Wal RM, van Veldhuisen DJ, van Gilst WH, Voors AA. Addition of an angiotensin receptor blocker to full-dose ACE-inhibition: Controversial or common sense? Eur Heart J 2005; 26: 2361–2367.

5.  5. Akazawa H, Komuro I. Mechanical stress induces cardiomyocyte hypertrophy through agonist-independent activation of angiotensin II type 1 receptor. In: Kamkin A, Kiseleva I, editors. Mechanosensitivity of the heart. Dordrecht, the Netherlands: Springer, 2010; 83–95.

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