Effects of the Factor Xa Inhibitor, Fondaparinux, on the Stability of Atherosclerotic Lesions in Apolipoprotein E-Deficient Mice
Author:
Affiliation:
1. Department of Cardiology, Zhongda Hospital, Medical School of Southeast University
Publisher
Japanese Circulation Society
Subject
Cardiology and Cardiovascular Medicine,General Medicine
Link
https://www.jstage.jst.go.jp/article/circj/79/11/79_CJ-15-0285/_pdf
Reference55 articles.
1. 1. Fenning RS, Wilensky RL. New insights into the vulnerable plaque from imaging studies. Curr Atheroscler Rep 2014; 16: 397.
2. 2. Bentzon JF, Otsuka F, Virmani R, Falk E. Mechanisms of plaque formation and rupture. Circ Res 2014; 114: 1852–1866.
3. 3. Zhou Q, Bea F, Preusch M, Wang H, Isermann B, Shahzad K, et al. Evaluation of plaque stability of advanced atherosclerotic lesions in apoE-deficient mice after treatment with the oral factor Xa inhibitor rivaroxaban. Mediators Inflamm 2011; 2011: 432080.
4. 4. Jobi K, Rauch BH, Dangwal S, Freidel K, Doller A, Eberhardt W, et al. Redox regulation of human protease-activated receptor-2 by activated factor X. Free Radic Biol Med 2011; 51: 1758–1764.
5. 5. Borensztajn K, Stiekema J, Nijmeijer S, Reitsma PH, Peppelenbosch MP, Spek CA. Factor Xa stimulates proinflammatory and profibrotic responses in fibroblasts via protease-activated receptor-2 activation. Am J Pathol 2008; 172: 309–320.
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