Real-World Effectiveness and Tolerability of Tolvaptan in Patients With Heart Failure ― Final Results of the Samsca Post-Marketing Surveillance in Heart Failure (SMILE) Study ―

Author:

Kinugawa Koichiro1,Sato Naoki2,Inomata Takayuki3,Yasuda Moriyoshi4,Shimakawa Toshiyuki5,Fukuta Yasuhiko5

Affiliation:

1. Second Department of Internal Medicine, University of Toyama

2. Department of Cardiology and Intensive Care Unit, Nippon Medical School Musashi-Kosugi Hospital

3. Department of Cardiology, Kitasato University Kitasato Institute Hospital

4. Department of Pharmacovigilance, Otsuka Pharmaceutical Co., Ltd.

5. Otsuka Pharmaceutical Co., Ltd.

Publisher

Japanese Circulation Society

Subject

Cardiology and Cardiovascular Medicine,General Medicine

Reference26 articles.

1. 1. Okura Y, Ramadan MM, Ohno Y, Mitsuma W, Tanaka K, Ito M, et al. Impending epidemic: Future projection of heart failure in Japan to the year 2055. Circ J 2008; 72: 489–491.

2. 2. Sato N, Kajimto K, Keida T, Mizuno M, Minami Y, Yumino D, et al. Clinical features and outcome in hospitalized heart failure in Japan (from the ATTEND registry). Circ J 2013; 77: 944–951.

3. 3. Ahmad T, Jackson K, Rao VS, Tang WHW, Brisco-Bacik MA, Chen HH, et al. Worsening renal function in patients with acute heart failure undergoing aggressive diuresis is not associated with tubular injury. Circulation 2018; 137: 2016–2028.

4. 4. Guidelines for diagnosis and treatment of acute and chronic heart failure (JCS 2017/JHFS 2017 [in Japanese]). https://www.mhlw.go.jp/file/05-Shingikai-10901000-Kenkoukyoku-Soumuka/0000202651.pdf (accessed February 20, 2019).

5. 5. Yamamura Y, Nakamura S, Itoh S, Hirano T, Onogawa T, Yamashita T, et al. OPC-41061, a highly potent human vasopressin V2-receptor antagonist: Pharmacological profile and aquaretic effect by single and multiple oral dosing in rats. J Pharmacol Exp Ther 1998; 287: 860–867.

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