Control of Heart Rate in Infant and Child Tachyarrhythmia With Reduced Cardiac Function Using Landiolol (HEARTFUL) ― Results of a Prospective, Multicenter, Uncontrolled Clinical Study ―

Author:

Sagawa Koichi1,Suzuki Tsugutoshi2,Takei Kohta3,Miura Masaru4,Ueda Hideaki5,Horigome Hitoshi6,Ono Hiroshi7,Ohashi Naoki8,Sato Seiichi9,Fukunaga Hideo10,Aoki Hisaaki11,Miyazaki Aya12,Sakaguchi Heima13,Morishima Eiichiro14,Oki Kaori15,Sumitomo Naokata16

Affiliation:

1. Department of Pediatric Cardiology, Cardiovascular Center, Fukuoka Children’s Hospital

2. Department of Pediatric Electrophysiology, Osaka City General Hospital

3. Department of Pediatric Cardiology, Nagano Children’s Hospital

4. Division of Cardiology, Tokyo Metropolitan Children’s Medical Center

5. Department of Cardiology, Kanagawa Children’s Medical Center

6. Department of Child Health, Faculty of Medicine, University of Tsukuba

7. Division of Cardiology, National Center for Child Health and Development

8. Department of Pediatric Cardiology, Japan Community Healthcare Organization Chukyo Hospital

9. Department of Pediatric Cardiology, Okinawa Prefectural Nanbu Medical Center & Children’s Medical Center

10. Department of Pediatrics, Juntendo University Faculty of Medicine

11. Department of Pediatric Cardiology, Osaka Women’s and Children’s Hospital

12. Division of Congenital Heart Disease, Department of Transition Medicine, Shizuoka General Hospital

13. Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center

14. Department of Statistical Analysis, Ono Pharmaceutical Co., Ltd.

15. Clinical Development Planning, Ono Pharmaceutical Co., Ltd.

16. Department of Pediatric Cardiology, Saitama Medical University International Medical Center

Publisher

Japanese Circulation Society

Subject

Cardiology and Cardiovascular Medicine,General Medicine

Reference30 articles.

1. 1. Brugada J, Blom N, Sarquella-Brugada G, Blomstrom-Lundqvist C, Deanfield J, Janousek J, et al. Pharmacological and non-pharmacological therapy for arrhythmias in the pediatric population: EHRA and AEPC-Arrhythmia Working Group joint consensus statement. Europace 2013; 15: 1337–1382, doi:10.1093/europace/eut082.

2. 2. Paul T, Bertram H, Bökenkamp R, Hausdorf G. Supraventricular tachycardia in infants, children and adolescents: Diagnosis, and pharmacological and interventional therapy. Paediatr Drugs 2000; 2: 171–181, doi:10.2165/00128072-200002030-00002.

3. 3. Brugada J, Katritsis DG, Arbelo E, Arribas F, Bax JJ, Blomström-Lundqvist C, et al. 2019 ESC guidelines for the management of patients with supraventricular tachycardia: The Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC). Eur Heart J 2020; 41: 655–720, doi:10.1093/eurheartj/ehz467.

4. 4. Page RL, Joglar JA, Caldwell MA, Calkins H, Conti JB, Deal BJ, et al. 2015 ACC/AHA/HRS guideline for the management of adult patients with supraventricular tachycardia: Executive summary: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol 2016; 67: 1575–1623, doi:10.1016/j.jacc.2015.09.019.

5. 5. Sumitomo N, Iwamoto M, Ushinohama H, Yoshinaga M, Izumida N, Yasuda T, et al. Guideline for diagnosis and treatment of pediatric arrhythmia. Pediatr Cardiol Cardiac Surg 2010; 26: 1–62 [in Japanese].

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