Do You Prescribe PCSK9 Inhibitors Properly?
Author:
Affiliation:
1. Department of Clinical Laboratory Technology, Faculty of Medical Science, Juntendo University
Publisher
Japanese Circulation Society
Link
https://www.jstage.jst.go.jp/article/circj/advpub/0/advpub_CJ-24-0186/_pdf
Reference11 articles.
1. 1. Abifadel M, Varret M, Rabes JP, Allard D, Ouguerram K, Devillers M, et al. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat Genet 2003; 34: 154–156.
2. 2. Horton JD, Cohen JC, Hobbs HH. Molecular biology of PCSK9: Its role in LDL metabolism. Trends Biochem Sci 2007; 32: 71–77.
3. 3. Lambert G, Charlton F, Rye KA, Piper DE. Molecular basis of PCSK9 function. Atherosclerosis 2009; 203: 1–7.
4. 4. Zhao Z, Tuakli-Wosornu Y, Lagace TA, Kinch L, Grishin NV, Horton JD, et al. Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote. Am J Hum Genet 2006; 79: 514–523.
5. 5. Hooper AJ, Marais AD, Tanyanyiwa DM, Burnett JR. The C679X mutation in PCSK9 is present and lowers blood cholesterol in a Southern African population. Atherosclerosis 2007; 193: 445–448.
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