Endogenous Adenosine May Be Related to Left Ventricular Dysfunction, Dilation, and Wall Thinning in Patients With Heart Disease

Author:

Kinomura Yujiro1,Tanaka Toshiki1,Aoyama Takuma1,Hatasa Masanori1,Minatoguchi Shingo1,Iwasa Masamitsu1,Yamada Yoshihisa1,Nawa Takahide1,Kanamori Hiromitsu1,Kawasaki Masanori1,Esaka Yukihiro2,Uno Bunji2,Nishigaki Kazuhiko1,Minatoguchi Shinya1

Affiliation:

1. Department of Cardiology, Gifu University Graduate School of Medicine

2. Laboratory of Pharmaceutical Analytical Chemistry, Gifu Pharmaceutical University

Publisher

Japanese Circulation Society

Subject

Cardiology and Cardiovascular Medicine,General Medicine

Reference16 articles.

1. 1. Liu GS, Thornton JD, Van Winkle DM, Stanley AWH, Olsson RA, Downey JM. Protection against infarction afforded by preconditioning is mediated by A1-adenosine receptors in rabbit heart. Circulation 1991; 84: 350–356.

2. 2. Thornton JD, Thornton CS, Downey JM. Effect of adenosine receptor blockade: Preventing protective preconditioning depends on time of initiation. Am J Physiol 1993; 265: H504–H508.

3. 3. Thornton JD, Liu GS, Olson RA, Downey JM. Intravenous pretreatment with A1-selective adenosine analogues protects the heart against infarction. Circulation 1992; 85: 659–665.

4. 4. Tsuchida A, Liu GS, Wilborn WH, Downey JM. Pretreatment with the adenosine A1 selective agonist, 2-chloro-N6-cyclo-N6-cyclopentyladenosine (CCPA), causes a sustained limitation of infarct size in rabbits. Cardiovasc Res 1993; 27: 652–656.

5. 5. Bai Y, Muquir, Murakami H, Iwasa M, Sumi S, Yamada Y, et al. Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: Focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels. Clin Exp Pharmacol Physiol 2011; 38: 658–665.

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