Bilateral Arm Gangrene Associated With Heparin-Induced Thrombocytopenia After Extracorporeal Cardiopulmonary Resuscitation

Author:

Ito Kansuke1,Isogai Toshiaki1,Takada Makiko2,Tatsumi Tetsushi3,Enatsu Kazuaki4,Tanaka Hiroyuki1,Tejima Tamotsu1

Affiliation:

1. Department of Cardiology, Tokyo Metropolitan Tama Medical Center

2. Department of Anesthesia, Tokyo Metropolitan Tama Medical Center

3. Department of Orthopedic Surgery, Tokyo Metropolitan Tama Medical Center

4. Department of Pathology, Tokyo Metropolitan Tama Medical Center

Publisher

Japanese Circulation Society

Subject

Cardiology and Cardiovascular Medicine,General Medicine

Reference8 articles.

1. 1. Martel N, Lee J, Wells PS. Risk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: A meta-analysis. Blood 2005; 106: 2710–2715.

2. 2. Goel R, Ness PM, Takemoto CM, Krishnamurti L, King KE, Tobian AA. Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality. Blood 2015; 125: 1470–1476.

3. 3. Olah Z, Kerenyi A, Kappelmayer J, Schlammadinger A, Razso K, Boda Z. Rapid-onset heparin-induced thrombocytopenia without previous heparin exposure. Platelets 2012; 23: 495–498.

4. 4. Krauel K, Weber C, Brandt S, Zahringer U, Mamat U, Greinacher A, et al. Platelet factor 4 binding to lipid A of Gram-negative bacteria exposes PF4/heparin-like epitopes. Blood 2012; 120: 3345–3352.

5. 5. Lo GK, Juhl D, Warkentin TE, Sigouin CS, Eichler P, Greinacher A. Evaluation of pretest clinical score (4 T’s) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings. J Thromb Haemost 2006; 4: 759–765.

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