Rationale and Design of the Effect of Ivabradine on Exercise Tolerance in Patients With Chronic Heart Failure (EXCILE-HF) Trial　― Protocol for a Multicenter Randomized Controlled Trial ―-Reference-Cited by-同舟云学术

Rationale and Design of the Effect of Ivabradine on Exercise Tolerance in Patients With Chronic Heart Failure (EXCILE-HF) Trial　― Protocol for a Multicenter Randomized Controlled Trial ―

Published:2023-04-10 Issue:4 Volume:5 Page:157-161
ISSN:2434-0790
Container-title:Circulation Reports
language:en
Short-container-title:Circ Rep

Author:

Shiga Tsuyoshi¹,Suzuki Tsuyoshi²,Kida Keisuke³,Suzuki Atsushi²,Kohno Takashi⁴,Ushijima Akiko⁵,Kiuchi Shunsuke⁶,Ishii Shunsuke⁷,Murata Makoto⁸,Ijichi Takeshi⁹,Suzuki Makoto¹⁰,Nishikawa Masako¹¹,

Affiliation:

1. Department of Clinical Pharmacology and Therapeutics, The Jikei University School of Medicine

2. Department of Cardiology, Tokyo Women’s Medical University

3. Department of Pharmacology, St. Marianna University School of Medicine

4. Department of Cardiovascular Medicine, Kyorin University Faculty of Medicine

5. Division of Cardiology, Department of Medicine, Tokai University Hachioji Hospital

6. Department of Cardiovascular Medicine, Toho University Graduate School of Medicine

7. Department of Cardiovascular Medicine, Kitasato University School of Medicine

8. Department of Cardiology, Gunma Prefectural Cardiovascular Center

9. Department of Cardiology, Tokai University School of Medicine

10. Department of Cardiology, Yokohama Minami Kyosai Hospital

11. Clinical Research Support Center, The Jikei University School of Medicine

Publisher

Japanese Circulation Society

Subject

Marketing,Organizational Behavior and Human Resource Management,Strategy and Management,Drug Discovery,Pharmaceutical Science,Pharmacology

Link

https://www.jstage.jst.go.jp/article/circrep/5/4/5_CR-22-0134/_pdf

Reference15 articles.

1. 1. Roger VL. Epidemiology of heart failure. Circ Res 2013; 113: 646–659.

2. 2. McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, et al. 2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 2021; 42: 3599–3726.

3. 3. Tsutsui H, Isobe M, Ito H, Ito H, Okumura K, Ono M, et al. JCS 2017/JHFS 2017 guideline on diagnosis and treatment of acute and chronic heart failure: Digest version. Circ J 2019; 83: 2084–2184.

4. 4. DiFrancesco D, Camm JA. Heart rate lowering by specific and selective I(f) current inhibition with ivabradine: A new therapeutic perspective in cardiovascular disease. Drugs 2004; 64: 1757–1765.

5. 5. Swedberg K, Komajda M, Böhm M, Borer JS, Ford I, Dubost-Brama A, et al. Ivabradine and outcomes in chronic heart failure (SHIFT): A randomised placebo-controlled study. Lancet 2010; 376: 875–885.