Level of lipid profile and liver enzyme of diabetic male rats induced by streptozotocin treated with forxiga

Abstract

The present study including study Level of lipid profile and liver enzyme of diabetic male rats induced by streptozotocin The study was carried out in the animal house of the Biology Department, College of Science, University of Thi-Qar ,Iraq. Thirty lab male rats were used in this study, and divided into five groups (6 rats for each group). Thirty male rats (190-210 gm) were randomly divided into five groups and placed in cages according to the groups, containing 6 rats per group as following. Group1, considered as the negative control group, given food and water for a period of 30 days. Group 2, served as the diabetic positive control, given streptozotocin were injected I.P. 60 mg/kg b.w. as a single dose with food and water for 15 days. Group 3, received streptozotocin were injected I.P (60 mg/kg) with food and water for 15 days, then treated with forxiga 1mg/kg administrated orally every day for a period of 15 days. Group 4, given were injected I.P streptozotocin (60 mg/kg) with s food and Water for 30 days. Group 5, received streptozotocin were injected I.P (60 mg/kg) with food and water. Then treated with forxiga1mg/kg administrated orally every day for a period of 15 day. At the end of experimental, all rats were euthanized, blood sample were obtained for bio chemical parameters.