ANTHROPOLOGICAL AND BIOCHEMICAL METABOLIC FACTORS IN THE NORMOGLYCEMIC, PRE-DIABETIC, AND DIABETIC METABOLIC POPULATION

Abstract

Background: The term "metabolic syndrome" (MetS) describes a collection of risk factors with metabolic origins that increase the chance of developing type 2 diabetes and cardiovascular disease (CVD). Diabetes is becoming more prevalent in underdeveloped countries, which challenges already limited health expenditures. Aim and Objective: To determine the burden of anthropometric and biochemical metabolic risk factors in normoglycemic, pre diabetics and diabetics metabolic population. Material and Methods: Study conducted in Physiology Department at RUHS College of Medical Sciences and associated hospital, Jaipur, after receiving the Ethical Clearance. The study's sample size was 300. Parameters recorded for data collection: anthropometric (Body Mass Index, Waist Hip Ratio), Blood pressure, biochemical (Fasting blood glucose, HbA1C, Lipid profile parameters). Result: 300 metabolic syndrome subjects were divided into three groups based on their Fasting Blood Glucose level and HbA1C level according to the American Diabetes Association for Diabetes Classification as normal [79 (26.33%)], pre-diabetic [85 (28.33%)], and diabetic [136 (45.33%)].There was significant difference of mean values of age, Waist Hip Ratio, Systolic Blood Pressure, Diastolic Blood Pressure, Fasting Blood Glucose, HbA1C, total cholesterol, High Density Lipoprotein, Low Density Lipoprotein and Triglyceride in three groups. Conclusion: According to the findings of the current study, the metabolic population of pre-diabetics and diabetics has a greater prevalence of metabolic risk factors. The metabolic risk factors grows when fasting blood glucose and HbA1C levels rise. It can also be said that these risk factors contribute to the onset of diabetes, which leads to metabolic syndrome.