Guidance on harmonised methodologies for human health, animal health and ecological risk assessment of combined exposure to multiple chemicals

Author:

,More Simon John,Bampidis Vasileios,Benford Diane,Bennekou Susanne Hougaard,Bragard Claude,Halldorsson Thorhallur Ingi,Hernández‐Jerez Antonio F,Koutsoumanis Konstantinos,Naegeli Hanspeter,Schlatter Josef R,Silano Vittorio,Nielsen Søren Saxmose,Schrenk Dieter,Turck Dominique,Younes Maged,Benfenati Emilio,Castle Laurence,Cedergreen Nina,Hardy Anthony,Laskowski Ryszard,Leblanc Jean Charles,Kortenkamp Andreas,Ragas Ad,Posthuma Leo,Svendsen Claus,Solecki Roland,Testai Emanuela,Dujardin Bruno,Kass George EN,Manini Paola,Jeddi Maryam Zare,Dorne Jean‐Lou CM,Hogstrand Christer

Publisher

Wiley

Subject

Plant Science,Veterinary (miscalleneous),Animal Science and Zoology,Microbiology,Food Science,Parasitology

Reference172 articles.

1. Algal toxicity of nitrobenzenes: Combined effect analysis as a pharmacological probe for similar modes of interaction;Altenburger;Environmental Toxicology and Chemistry,2005

2. Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment;Ankley;Environmental Toxicology and Chemistry,2010

3. ATSDR (Agency for Toxic Substances and Disease Registry), 2004. Guidance Manual for the Assessment of Joint Toxic Action of Chemical Mixtures. US Department of Health and Human Services, 107.

4. ATSDR (Agency for Toxic Substances and Disease Registry), 2018. Framework for assessing health impacts of multiple chemicals and other stressors (update). Available online: https://www.atsdr.cdc.gov/interactionprofiles/ip-ga/ipga.pdf

5. Azimonti G, Galimberti F, Marchetto F, Menaballi L, Ullucci S, Pellicioli F, Alessandra C, Lidia C, Alessio I, Angelo M, de Boer W and van der Voet H, 2015. Comparison of NOEC values to EC10/EC20 values, including confidence intervals, in aquatic and terrestrial ecotoxicological risk assessment. EFSA Supporting Publications, 12(12), p.906E.

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