Biologicals in severe chronic rhinosinusitis with nasal polyps: translation to clinical practice while waiting for head-to-head studies
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Published:2023-03-01
Issue:0
Volume:0
Page:0-0
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ISSN:0300-0729
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Container-title:Rhinology Journal
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language:
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Short-container-title:Rhin
Author:
Boechat J L,Sousa-Pinto B,Delgado L,Silva D
Abstract
Dear Editor: Chronic rhinosinusitis with nasal polyps (CRSwNP) affects 1.0-2.6% of the population (1) and results in relevant direct and indirect costs. Recently, several randomized controlled trials (RCTs) with Type 2-targeting biologicals (anti-IL4Rα, anti-IL5R, anti-IL5 and anti-IgE) opened a new treatment field for patients refractory to first-line treatments (2,3).
Subject
Otorhinolaryngology,General Medicine