USE OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS ON PERIODONTAL THERAPY IN PATIENTS WITH COMORBID PATHOLOGY
Author:
Ssablina Svetlana1, Elovicova Tat'yana1, Griroriev Sergey1, Dorokhina Ksenya1, Yepishova Anna1, Chagay Andrey1, Mirsaev Timur1, Ivanova Valeria1, Balakina Darjia2
Affiliation:
1. Ural State Medical University 2. South Ural State Medical Institute
Abstract
Subject. This paper covers the main aspects of non-steroidal anti-inflammatory drugs (NSAIDs) used on periodontal therapy in patients with cormobid pathology.
Objectives. A domestic and foreign literature review on effects of NSAIDs on periodontal therapy in patients with cormobid pathology.
Methodology. The literature review is based on the source literature available over the past five years starting 2015 by PubMed keywords in order to summarize the subject information.
Conclusion. NSAIDs, therefore, remain the most essential medications on etiotropic, pathogenetic and symptomatic therapy of dental disorders. NSAIDs can help manage pain syndrome, control inflammation responses and regeneration with indulating inflammation-induced tissue destruction, prevent unnecessary complications during basic and supportive periodontal therapy including invasive techniques. Systemic and localized use of NSAIDs in the complex periodontal therapy based on the rational choice of the drug and the appropriate dose selection considering patient’s comorbidities must be necessarily supported by the dentist’s knowledge of pharmacodynamics and NSAIDs classifications with Clinical Guidance on rational use of NSAIDs (2015, revised 2018) and Clinical Guidance on comorbid pathology (2019) taken as the basis. These, therefore, will ensure the personified approach, efficacy and safety of NSAID use in patients.
Publisher
TIRAZH Publishing House
Reference35 articles.
1. Голобородова И.В., Сметнева Н.С., Васильев Ю.Л., Погосян А.В. Нестероидные противовоспалиельные препараты в стоматологии: особенности назначения пациентам с сопутствующими заболеваниями почек. Медицинский алфавит. 2017;24(3):20-22. [I.V. Goloborodova, N.S. Smetneva, Yu.L. Vasiliev, A.V. Pogosyan. Nonsteroidal anti-inflammatory drugs in dentistry: prescription features in patients with concomitant renal disease. Medical alphabet. 2017;3(24):20-22. (In Russ.)]. https://www.med-alphabet.com/jour/article/view/309?locale=ru_RU, Goloborodova I.V., Smetneva N.S., Vasil'ev Yu.L., Pogosyan A.V. Nesteroidnye protivovospaliel'nye preparaty v stomatologii: osobennosti naznacheniya pacientam s soputstvuyuschimi zabolevaniyami pochek. Medicinskiy alfavit. 2017;24(3):20-22. [I.V. Goloborodova, N.S. Smetneva, Yu.L. Vasiliev, A.V. Pogosyan. Nonsteroidal anti-inflammatory drugs in dentistry: prescription features in patients with concomitant renal disease. Medical alphabet. 2017;3(24):20-22. (In Russ.)]. https://www.med-alphabet.com/jour/article/view/309?locale=ru_RU 2. Саблина С.Н., Еловикова Т.М., Григорьев С.С. Роль витамина D в поддержании здоровья полости рта (литературный обзор). Проблемы стоматологии. 2020;16(4):25-34. [S.N. Sablina, T.M. Elovikova, S.S. Grigoriev. The role of vitamin D in maintaining oral health (literature review). Actual Problems in Dentistry. 2020;16(4):25-34. (In Russ.)]. https://doi.org/10.18481/2077-7566-20-16-4-25-34, Sablina S.N., Elovikova T.M., Grigor'ev S.S. Rol' vitamina D v podderzhanii zdorov'ya polosti rta (literaturnyy obzor). Problemy stomatologii. 2020;16(4):25-34. [S.N. Sablina, T.M. Elovikova, S.S. Grigoriev. The role of vitamin D in maintaining oral health (literature review). Actual Problems in Dentistry. 2020;16(4):25-34. (In Russ.)]. https://doi.org/10.18481/2077-7566-20-16-4-25-34 3. Дядык А., Куглер Т., Цыба И. Нефротоксичность нестероидных противовоспалительных препаратов: механизмы, клиника, профилактика. Врач. 2017;11:7-12. [A. Djadyk, T. Kugler, I. Tsyiba. Nephrotoxicity of nonsteroidal anti-inflammatory drugs: mechanisms, clinical implications, prophylaxis. Vrach. 2017;11:7-12. (In Russ.)]. https://www.elibrary.ru/item.asp?id=30691109, Dyadyk A., Kugler T., Cyba I. Nefrotoksichnost' nesteroidnyh protivovospalitel'nyh preparatov: mehanizmy, klinika, profilaktika. Vrach. 2017;11:7-12. [A. Djadyk, T. Kugler, I. Tsyiba. Nephrotoxicity of nonsteroidal anti-inflammatory drugs: mechanisms, clinical implications, prophylaxis. Vrach. 2017;11:7-12. (In Russ.)]. https://www.elibrary.ru/item.asp?id=30691109 4. Еловикова Т.М., Саблина С.Н., Ермишина Е.Ю., Кощеев А.С. Анализ влияния лечебно-профилактической зубной пасты, содержащей novamin, на состояние органов полости рта у молодых курильщиков табака. Стоматология. 2021;100(3):35-39. [T.M. Elovikova, S.N. Sablina, E.Yu. Ermishina, A.S. Koscheev. Study on effects of theraupetic and prophilactic toothpaste with novamin on oral cavity in young tobacco users. Dentistry. 2021;100(3):35-39. (In Russ.)]. doi:10.17116/stomat202110003135, Elovikova T.M., Sablina S.N., Ermishina E.Yu., Koscheev A.S. Analiz vliyaniya lechebno-profilakticheskoy zubnoy pasty, soderzhaschey novamin, na sostoyanie organov polosti rta u molodyh kuril'schikov tabaka. Stomatologiya. 2021;100(3):35-39. [T.M. Elovikova, S.N. Sablina, E.Yu. Ermishina, A.S. Koscheev. Study on effects of theraupetic and prophilactic toothpaste with novamin on oral cavity in young tobacco users. Dentistry. 2021;100(3):35-39. (In Russ.)]. doi:10.17116/stomat202110003135 5. Иорданишвили А.К., Дягилев А.И., Рисованная О.Н., Скориков В.Ю., Попков В.Л. Особенности применения нестероидных противовоспалительных лекарственных средств в стоматологической практике. Кубанский научный медицинский вестник. 2018;25(5):48-52. [A.K. Iordanishvili, A.I. Dyagilev, O.N. Risovannaya, V.Yu. Skorikov, V.L. Popkov. Features of using nonsteroidal anti-inflammatory drugsin dental practice. Kuban Scientific Medical Bulletin. 2018;25(5):48-52. (In Russ.)]. https://cyberleninka.ru/article/n/osobennosti-primeneniya-nesteroidnyh-protivovospalitelnyh-sredstv-v-stomatologicheskoy-praktike, Iordanishvili A.K., Dyagilev A.I., Risovannaya O.N., Skorikov V.Yu., Popkov V.L. Osobennosti primeneniya nesteroidnyh protivovospalitel'nyh lekarstvennyh sredstv v stomatologicheskoy praktike. Kubanskiy nauchnyy medicinskiy vestnik. 2018;25(5):48-52. [A.K. Iordanishvili, A.I. Dyagilev, O.N. Risovannaya, V.Yu. Skorikov, V.L. Popkov. Features of using nonsteroidal anti-inflammatory drugsin dental practice. Kuban Scientific Medical Bulletin. 2018;25(5):48-52. (In Russ.)]. https://cyberleninka.ru/article/n/osobennosti-primeneniya-nesteroidnyh-protivovospalitelnyh-sredstv-v-stomatologicheskoy-praktike
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