Dynamics of the lipoperoxidation process in the oral fluid of patients with chronic generalized periodontitis with the complex application of laser therapy and interval hypoxic training

Abstract

The performed research is devoted to the study of lipid peroxidation processes in patients with chronic generalized periodontitis under the conditions of the course application of infrared laser therapy and normobaric interval hypoxic training. The results of the study allow us to conclude that the development of inflammatory destructive processes in periodontal tissues closely correlates with manifestations of oxidative stress, which develops as a result of an imbalance in the pro-oxidants-antioxidants system. Supplementing the standard therapy of chronic generalized periodontitis with the course use of physiotherapeutic factors in the mono-influence mode is accompanied by an increase in the potential of the antioxidant protection of the oral cavity. The complex use of physiofactors contributes to an increase in the activity of the antioxidant system, realized through the mechanisms of functional potentiation. The close relationship revealed between lipid peroxidation products and index characteristics of dental status, reflecting the pathogenetic role of pro-oxidant factors in the development of chronic generalized periodontitis, allows us to consider biomarkers of peroxide metabolism and the antioxidant protection coefficient as criteria for the effectiveness of the treatment.