Controlled and uncontrolled physicochemical quality indicators of 0.9 % sodium chloride of various manufacturers-Reference-Cited by-同舟云学术

Controlled and uncontrolled physicochemical quality indicators of 0.9 % sodium chloride of various manufacturers

Published:2020-06-01 Issue:3 Volume: Page:6-11
ISSN:
Container-title:Novejshie zarubezhnye i otechestvennye lekarstvennye preparaty: farmakoterapija, farmakodinamika, farmakokinetika (Newest Foreign and Domestic Preparations: Pharmacotherapy, Pharmacodynamics, Pharmacokinetics)
language:ru
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Author:

Kasatkin Anton¹^ORCID,Nigmatullina Anna¹^ORCID,Kopytov Mikhail¹

Affiliation:

1. Izhevsk State Medical Academy of the Ministry of Health of the Russian Federation

Abstract

The article presents the results of studies of osmolality and pH of 0,9 % sodium chloride of various manufacturers. To obtain data on the pH value, the data used in the passports are used, and the indicators of its osmolality are de- termined using laboratory tests. 0,9 % sodium chloride from different manufacturers has different pH and osmolality. Knowing the actual values of physico-chemical parameters can increase the accuracy of the results of future clinical studies, which compare the pharmacokinetics and pharmacodynamics of modern plasma-substituting solutions and a solution of 0,9 % sodium chloride.

Publisher

PANORAMA Publishing House

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