Distal subtotal resection and gastrectomy in the treatment of patients with gastric cancer. A critical review of meta-analyses-Reference-Cited by-同舟云学术

Distal subtotal resection and gastrectomy in the treatment of patients with gastric cancer. A critical review of meta-analyses

Published:2020-02-01 Issue:1-2 Volume: Page:26-35
ISSN:2074-0190
Container-title:Hirurg (Surgeon)
language:ru
Short-container-title:

Author:

Panin S.¹^ORCID,Postolov M.¹^ORCID,Kovalenko N.¹^ORCID,Beburishvili A.¹,Tolstopyatov S.¹^ORCID

Affiliation:

1. Volgograd State Medical University

Abstract

The purpose of the work is to study the evidence base by comparing the results of distal subtotal resection and gastrectomy with D2 lymphadenectomy in patients with distal gastric cancer. Materials and methods. Three meta-analyses were selected during the systematic review process. Their validity assessment and critical analysis were carried out using the recommendations of the Cochrane community. Results. The greatest heterogeneity was noted in calculations of the frequency of postoperative complications. This indicator ranges from 1.1 % to 22 %. Postoperative mortality ranges from 0.6 % to 2.9 %. The overall five-year survival rate after gastrectomy is 49.6 %–53.9 %, after distal subtotal resection — 55.9 %–63.9 %. A large number of systematic biases in completed meta-analyses reduces the degree of reliability of the evidence base in this matter to the level 2 of evidence. Conclusion. Further evidence-based level 1 studies are needed to compare the results of distal subtotal resection and gastrectomy in patients with distal gastric cancer.

Publisher

PANORAMA Publishing House

Subject

General Chemical Engineering

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