Clinical and morphological forms of tuberculous peritonitis

Abstract

On the basis of a specialized tuberculosis surgical department, a study was conducted aimed at identifying the clinical and morphological features of the course of the disease in 91 patients with tuberculous peritonitis. It has been established that the morphogenesis of tuberculous peritonitis directly depends on such factors as the initial immune status of the patient, the virulence of the pathogen, the type of tissue reaction, and some genetically determined features of the coagulation and anticoagulation systems and fibroblast activity. A direct correlation of the morphological variant of peritonitis with the form of the clinical course of the disease and the development of surgical complications was noted. Based on the data obtained and the patterns identified, a functional classification of tuberculous peritonitis is proposed, taking into account the prevailing morphological variant of peritoneal tuberculosis, the phases of activity and the development of complications requiring surgical interventions. The developed classification has a clear practical focus, allows you to visually determine the morphological variant of the pathological process, its activity (according to the totality of indirect factors), as well as assess the presence of complications requiring surgical treatment.