Differences in the mechanisms of therapeutic action of platelet-rich plasma in the treatment of various joints-Reference-Cited by-同舟云学术

Differences in the mechanisms of therapeutic action of platelet-rich plasma in the treatment of various joints

Published:2021-07-12 Issue:8 Volume: Page:30-37
ISSN:2074-9600
Container-title:Spravočnik vrača obŝej praktiki (Journal of Family Medicine)
language:ru
Short-container-title:

Author:

Teplov Oleg Vadimovich¹^ORCID,Teplov Aleksandr Yurievich²

Affiliation:

1. SAHI RCH MH RT

2. FSBEI HE Kazan State Medical University of the Ministry of Health of Russia, Kazan, RT

Abstract

The paper presents the results of the application of the plasmolifting technique in the treatment of various types of musculoskeletal pathology and analyzes the possible mechanisms of the positive therapeutic effect of this technique. It is suggested that its success is in direct proportion to the composition of the tissues that make up a particular articular formation. It is supposed that the conditions for the positive therapeutic effect of the platelet auto-suspension technique include, first of all, the presence of a branched network of capillaries, which provides sufficient blood supply and, as a result, access to the sanitized tissue of granulocytic cells. The second condition is the presence of connective tissue formations containing basophils and mast cells, which, together with the endothelium of the above capillaries, secrete a sufficient amount of cytokines that trigger the therapeutic effect of this manipulation. A number of recommendations were made to increase the sanitizing effect of the plasmolifting technique on a specific joint formation.

Publisher

PANORAMA Publishing House

Reference25 articles.

1. Akhmerov R. R., Zarudii R. F., Makhmutova A. F., Khanin E. Iu. Autoplazma v lechenii vozrastnoi atrofii kozhi [Autoplasma in the treatment of age-related skin atrophy] // Naturoterapiia i gomeopatiia [Natural therapy and homeopathy]. 2006. No. 1 (8). P. 38–41. (In Russ.)

2. Khamidullin F. R., Akhmerov R. R. Primenenie tekhnologii PLASMOLIFTINGTM v travmatologii I vosstanovitelnoi meditsine [Application of PLASMOLIFTINGTM technology in traumatology and restorative medicine] // In the book: Regenerative medicine based on autologous plasma. Plasmolifting TM technology. Akhmerov R. R. Moscow, 2014. P. 85–102. (In Russ.)

3. Maiko O. Iu., Bagirova G. G. Funktsionalnye indeksy pri otsenke effektivnosti lecheniia gonartroza preparatami struktum i khondrolom [Functional indices in assessing the effectiveness of treatment of gonarthrosis with drugs struktum and chondrol] // Terapevticheskii arkhiv [Therapeutic archive]. 2006. Vol. 78. No. 6. P. 47–52. (In Russ.)

4. Kushnir V. A., Karateev D. E. Sovremennye vozmozhnosti lecheniia bolnykh osteoartritom: fokus na obogashchennuiu trombotsitami plazmu [Modern treatment options for patients with osteoarthritis: focus on platelet-rich plasma] // Effektivnaia farmakoterapiia [Effective Pharmacotherapy]. 2018. No. 33. P. 40–46. (In Russ.)

5. Shitikova A. S. Trombotsitarnyi gemostaz [Platelet hemostasis]. — SPb.: Publishing house of SPbGMU, 2000. — 227 p. (In Russ.)