Epidemiological trends in morbidity and issues of rotavirus vaccine prevention at the present stage

Abstract

The urgency of the problem of rotavirus infection is determined by the high incidence, complications, with the formation of chronic pathology and the possibility of fatal outcomes. The purpose of this work is to analyze the features of epidemiology of rotavirus infection in Russia. Materials and methods. A retrospective epidemiological analysis was carried out using official statistics. Results and discussion. The trend of a steady increase in incidence of rotavirus infection in Russia from 2001 to 2018 has been established. The territories with the highest incidence in Russia have been identified. Age groups with a high risk of rotavirus infection are children under 1 year and 1–2 year. The trends in the incidence of the disease in the age groups 3–6, 15–17, 18 years and older. Ongoing preventive measures do not have a significant impact on reducing the incidence of rotavirus infection. Circulating strains were established in territory of Russia. Conclusions. The analysis showed the high relevance of organization of rotavirus infection prevention system. The current restrictions on the coverage of rotavirus vaccination in Russian population do not allow effective control of epidemic process of this disease. therefore, it is extremely necessary to recommend the inclusion of rotavirus vaccination in the national calendar of preventive vaccinations of Russia. Most of antigenic G/P variants of rotaviruses circulating in Russia fully or partially correspond to composition of the Rota Tech vaccine, which makes it possible to predict high efficiency of its use in all the territories of our country.