Features of the circulation of gram-negative carbapenem-resistant microorganisms in different departments of a multidisciplinary hospital

Abstract

Purpose — to study the features of the circulation of gram-negative microorganisms resistant to carbapenems from the «ESKAPE» group among patients from different departments of the hospital. The study showed that every 132nd patient hospitalized in a somatic multidisciplinary hospital in Moscow is a source of carbapenem-resistant gram-negative microorganisms from the «ESKAPE» pathogens (0.76 % [95 % CI: 0.7–0.8]). It was established that P. aeruginosa prevailed in the structure of «ESKAPE» pathogens that demonstrated resistance to carbapenems — 46.4 % [95 % CI: 43.1–49.5]; K. pneumoniae — 28.5 % [95 % CI: 25.7–31.4] and A. baumanii — 12.3 % [95 % CI: 10.3–14.5], and the maximum frequency of their detection was recorded from patients of the pulmonology department — 8.32 % [95 % CI: 7.71–8.97]. The structure and frequency of detection of sources of infection in departments is shown. Thus, strains of P. aeruginosa — 5.07 % [95 % CI: 4.49–5.58] and K. pneumoniae — 1.83 % [95 % CI: 1.54–2,15], with a specific gravity of 60.91 % and 21.98 %. In surgical patients, detection of E. coli prevailed (46.88 %) with a frequency of 0.16 % [95 % CI: 0.12–0.2], in intensive care units (70.73 %) K. pneumoniae strains were more common 0.27 % [95 % CI: 0.21–0.35], urological also K. pneumoniae 0.26 % [95 % CI: 0.2–0.34], therapeutic A. baumannii 0.11 % [95 % CI: 0.07–0.16], with a specific gravity of 50 %.