Possibilities of structure modifying therapy of subcompensated gonarthrosis-Reference-Cited by-同舟云学术

Possibilities of structure modifying therapy of subcompensated gonarthrosis

Published:2022-11-20 Issue:11 Volume: Page:21-31
ISSN:
Container-title:Glavvrač (Chief Medical Officer)
language:
Short-container-title:Chief Medical Officer

Author:

Minasov T. B.^ORCID, ,Minasov B. S.^ORCID,Ginoyan A. O.^ORCID,Imaeva A. K.^ORCID,Vishnyakov D. S.,Nurlygayanov R. Z.^ORCID,Yakupova E. R.^ORCID, , , , , , , ,

Abstract

This study shows that a combined treatment regimen consisting of a NSAID group drug and a slow-acting chondroprotective agent has a positive effect in the therapy of subcompensated osteoarthritis of the knee joint. Diacerein has an anti-inflammatory effect and inhibits the activity of interleukin-1, interleukin-6, and TNF-alpha, as well as collagenase and elastase, which destroy the hyaline cartilage. However, the effect of the drug does not occur immediately, which justifies its combination with NSAIDs.

Publisher

PANORAMA Publishing House

Subject

General Engineering,General Engineering,General Engineering,General Engineering,General Engineering,General Engineering,General Engineering,General Engineering,General Engineering,General Computer Science,General Engineering,General Medicine

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