Determination of the efficacy of oncolytic viruses in combination with autophagy inducers to potentize cancer cell death

Author:

Kench U.S.ORCID, ,Spirin P.V.ORCID,Sologova S.S.ORCID, ,

Abstract

Purpose of the study: to determine and analyze the possibility of potentiation of virotherapy by combination with autophagy inducers.

Publisher

PANORAMA Publishing House

Reference4 articles.

1. 1. Pei-Hsin Cheng и др. Combination of autophagy inducer rapamycin and oncolytic adenovirus improves antitumor effect in cancer cells. DOI: 10.1186/1743-422X-10-293.

2. 2. Sarah R Klein и др. Critical Role of Autophagy in the Processing of Adenovirus Capsid-Incorporated Cancer- Specific Antigens. DOI: 10.1371/journal.pone.0153814.

3. 3. Meng S и др. Pharmacological modulation of autophagy enhances Newcastle disease virus-mediated oncolysis in drug-resistant lung cancer cells. DOI: 10.1186/1471 2407 14 551.

4. 4. QuanZhanga и др. Inactivated Sendai virus induces apoptosis and autophagy via the PI3K/Akt/mTOR/p70S6K pathway in human non-small cell lung cancer cells. DOI.org/10.1016/j.bbrc.2015.07.130.64 9 6 (In Russ.)

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