Correlation of manganese in hairs with some biochemical parameters in blood serum of pigs

Abstract

Currently, along with an in-depth study of the gene pool and the phenotype pool of farm animals of different breeds and species in the zones of their breeding, special attention is paid to the production of environmentally friendly and safe products of the agro-industrial complex for the end consumer. Therefore, water, feed, soil, animal organs and tissues are carefully monitored for the content of chemical elements. Manganese, like magnesium and other divalent ions, is a non-specific activator of enzymes: hydrolases, kinases, decarboxylases, etc. The absolute need for Mn is confirmed by the metalloenzymes pyruvate carboxylase of the liver mitochondria and muscle oxaloacetate carboxylase. The first contains four manganese atoms and four biotin molecules and catalyzes the carboxylation of pyruvic acid to oxaloacetic acid. The removal of Mn leads to the irreversible loss of enzyme activity, which is not restored with the subsequent introduction of the endogenous metal. The purpose of the research was to establish the correlations of the accumulation of manganese in the hairs with some biochemical parameters in the blood of pigs of Kemerovskaya breed. During the work the correlations of manganese in the hairs with some biochemical parameters of blood serum of pigs have been studied. When comparing the obtained data with the studies of other scientists, all the correlations were described except for the content of manganese in the hairs with serum chlorides (r=–0,43), since this correlation was not confirmed by the data of the scientific literature. A positive correlation has been established between the level of Mn with cholesterol and Mg at the level of 0,542 and 0,417, respectively. The change in the magnitude and direction of the correlation between the concentration of Mn in the hairs and the biochemical composition of the blood can be caused by some animal diseases.