Interval normobaric hypoxic therapy as a method of correction in neurological patients

Abstract

This article is devoted to the analysis of modern literature on the use of interval normobaric hypoxic therapy among neurological patients. Its relevance is determined by the need to find measures to prevent the negative effects of oxygen deficiency, as hypoxia is a key factor in the development of many pathological conditions in the human body and in the central nervous system in particular. Hypoxic effects of excessive strength or duration, leads to decompensation of adaptation mechanisms, triggers a chain of irreversible metabolic disorders that lead to cell death, destruction of intercellular and neural network interactions in the brain and, consequently,to the development of neurological deficit and disability ofthe patient.However,when the body adapts to hypoxia,which can be achieved by using interval normobaric hypoxic therapy, it is possible to achieve a positive effect in the correction of patients with various diseases of the central nervous system. We have considered both general mechanisms of the body’s defense formation during adaptation to hypoxia, and individualmechanisms related directly to the central nervous system. The role of biologicalmarkers and markers of oxidative stress determining the body’s individual response to oxygen deficiency has been evaluated. An analysis of studies evaluating the effect of interval normobaric hypoxic therapy on the course of such diseases as Alzheimer’s disease, Parkinson’s disease, discirculatory encephalopathy and the consequences of craniocerebral injuries was performed. It was found that properly performed interval normobaric hypoxic therapy contributes to the correction and compensation of impaired functions, improves the quality of life of patients and increases the adaptive reserve of the body to stressful influences.