Role of oxidative stress in the pathogenesis of postmenopausal osteoporosis (literature review)

Author:

Bulgakova S. V.1ORCID,Melikova A. V.2

Affiliation:

1. Samara State Medical University, Samara, Russia

2. «Klinika P’yati Blag», Samara, Russia

Abstract

Postmenopausal osteoporosis is a disease of great medical and social significance for the world population. At the same time, the underlying pathogenesis of this pathology is not fully understood. A large body of research suggests that endocrine changes associated with postmenopause can lead to disruption of redox homeostasis and oxidative stress that affects bone metabolism. This literature review analyzes the relationship between hypoestrogenemia, oxidative stress and postmenopausal osteoporosis, as well as methods for the prevention and treatment of these conditions.

Publisher

PANORAMA Publishing House

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