Experimental hydrops of labyrinth-Reference-Cited by-同舟云学术

Experimental hydrops of labyrinth

Published:2021-12-06 Issue:12 Volume: Page:37-43
ISSN:2075-0277
Container-title:Terapevt (General Physician)
language:ru
Short-container-title:

Author:

Kiselev Vladimir Vyacheslavovich¹,Pomukhin Dmitriy Valerievich²

Affiliation:

1. Department of Otorhinolaryngology, FSBEI HE Rostov State Medical University of the Ministry of Health of the Russian Federation

2. Department of Otorhinolaryngology, PHI Clinical Hospital «RZhD–Medicine», Rostov-on-Don

Abstract

Difficulties in approbation of drugs for the treatment of vestibular dysfunction are associated with a lack of knowledge of the mechanisms of its development. In particular, it is necessary to take into account the initial state of the vestibular analyzer, which significantly affects the research results. Therefore, the modeling of pathological processes that manifest in vestibular dysfunction is the optimal method for studying both its mechanisms and the effectiveness of medications for its relief. Endolymphatic hydrops is found in most diseases manifested by peripheral vestibular syndrome. We have proposed several models of endolymphatic hydrops in rats to study various aspects of its pathogenesis and approbate means of treating vestibular dysfunction.

Publisher

PANORAMA Publishing House

Reference10 articles.

1. Boiko N. V. Golovokruzhenie v praktike vracha [Vertigo in medical practice]. Zhurnal nevrologii i psikhiatrii imeni S. S. Korsakova [Journal of Neurology and Psychiatry named after S. S. Korsakov]. 2005;105 (1):74–77. (In Russ.) https://doi.org/:10.17116/otorino201782380–83

2. Boiko N. V. Golovokruzhenie v praktike vracha-terapevta [Vertigo in the practice of a general practitioner]. Lechashchii vrach [Attending Physician]. 2010; 4: 86. (In Russ.)

3. Peppard S. B. Effect of drug therapy on compensation from vestibular injury // Laryngoscope.— 2006. — Vol. 96, № 8. — P.878–898.

4. Herron DG. The ups and downs of motion sickness // Am J Nurs. — 2010. — Vol 110, N 12. — P.49–51.

5. Pomukhina A. N., Kiselev V. V. Morfologicheskaia kharakteristika eksperimentalnogo endolimfaticheskogo gidropsa [Morphological characteristics of experimental endolymphatic hydrops] // Vestn. otorinolar. [Bulletin of Otorhinolaryngology]. — 1989. — No. 5. — P. 30–35. (In Russ.)