Clinical and immunological efficacy of the drug Nobazit® (enisamium iodide) in the complex therapy of acute respiratory viral infections

Author:

Gizinger O. A.1ORCID

Affiliation:

1. Peoples Friendship University of Russia; Medical Institute, Moscow, Russia

Abstract

The term «acute respiratory viral infections» refers to a group of diseases whose etiological agents are respiratory viruses, mainly affecting the epithelium of the upper respiratory tract. The article presents the results of studying the effectiveness of the drug Nobazit® in 32 patients with body temperature > 37.5 °C having at least one catarrhal symptom (cough, rhinitis, or sore throat) and one symptom of intoxication (chills, sweating, malaise, weakness, or headache) who consulted a doctor within the first 48 hours from the onset of symptoms of an acute respiratory viral infection. The use of the drug Nobazit® (enisamium iodide) allowed to reduce the severity of clinical manifestations, eliminate lymphopenia, normalize factors of innate and adaptive immunity, and restore the receptor landscape of peripheral blood lymphocytes. The registered clinical and immunological efficacy of the drug Nobazit® allows recommending its inclusion in the complex therapy of acute respiratory infections.

Publisher

PANORAMA Publishing House

Reference21 articles.

1. Dolgushin I. I. Immunoprophylaxis of infectious diseases. Educational and methodological guide.I. I. Dolgushin, O. A. Gizinger, S. V. Luchinina. Chelyabinsk. 2014; 112.

2. Zaplatnikov A. L. Immunoprophylaxis and immunotherapy of acute respiratory infections in children. Attending physician. 2006; 9: 50–56.

3. Pshenichnaya N. Yu., et al. Overview of current and prospective directions of antiviral therapy for infl uenza and acute respiratory viral infections in Russia. Therapeutic archive. 2019; 91 (11): 105–109. https://doi.org/10.26442/00403660.2020.03.000572.

4. Vikulov G. Kh. Viral, bacterial respiratory infections, immunity and antibiotic therapy: what do they have in common? The view and recommendations of a clinical immunologist and infectious disease specialist. ConsiliumMedicum. 2015; 17 (11): 35–41.

5. Paevskaya O. A., Zuevskaya S. N., Nikiforov V. V., Belaya O. F., Kolaeva N. V., Nemilostiva E. A., Kanshina N. N., Turkadze K. A. Possibilities of etiotropic therapy in reducing the risks of severe or complicated course of SARS and infl uenza. RMJ. 30.04.2019; 1 (II): 77–80. Available at: https:// www.rmj.ru/articles/infektsiya/Vozmoghnosti_etiotropnoy_terapii_v_snighenii_riskov_razvitiya_tyaghelogo_ili_osloghnennogo_techeniya_ORVI_i_grippa/#ixzz6RIbNoXxe.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3