Affiliation:
1. Federal State Budgetary Educational Institution of Higher Education South Ural State Medical University of the Ministry of Health of the Russian Federation, Chelyabinsk
Abstract
The article presents the data from Russian and foreign literature on the state of humoral and cellular factors of local antimicrobial protection of the mucous membrane of the nasal cavity and paranasal sinuses in the pathogenesis of immune disorders in deviated septum. The role of cellular, humoral factors, and interreceptor interactions of cells of the respiratory, glandular epithelium, phagocytes, lymphocytes in pathological conditions of the nasal mucosa and paranasal sinuses was analyzed. The role of immune mechanisms in the development of pathological reactions in deviated septum is shown. The presented review will expand the understanding of the role of antimicrobial factors in the pathogenesis of immune disorders in deviated septum.
Publisher
PANORAMA Publishing House
Reference25 articles.
1. Zavgorodnaia E. G. Tsitokiny i ikh mesto v diagnostike i lechenii riada zabolevanii LOR-organov [Cytokines and their place in the diagnosis and treatment of a number of diseases of ENT organs]. Vestnik otorinolaringologii [Bulletin of otorhinolaryngology] 2008. 3: 74–76. https://doi.org/10.1789 6/rosakush20151514–8. (In Russ.).
2. Kato A, Hulse KE, Tan BK, Schleimer RP. B lymphocyte lineage cells and the respiratory system. The Journal of allergy and clinical immunology. 2013; 131 (4): 933–957. https://doi.org/10.1016/j.jaci. 2013.02.023
3. Doss М., White M. R., Tecle Т., Hartshorn K. L. Defensins and mucosal immunity.Journal of Leukocyte Biology. 2010..8: 79–92 https://doi.org/10.1189/jib. 069382
4. Expression of toll-like receptors in human endometrial cells and cell lines /S. L. Young, T. D..Lyddon, R. L. Jorgerson. American Journal of Reproductive Immunology. 2004. 52. 1: 67–73. https://doi.org/10.1155/2010/976024
5. Tyrnova E. V., Aleshina G. M, Ianov Iu. K. Sravnitelnaia otsenka ekspressii gena toll-podobnogo retseptora-2 v slizistoi obolochke verkhnikh dykhatelnykh putei [Comparative evaluation of the expression of the TOLL-like receptor-2 gene in the upper respiratory tract mucosa]. Rossiiskii fiziologicheskii zhurnal im. I. M. Sechenova [Russian physiological journal named after I. M. Sechenov]. (In Russ.). https://doi.org/10.1134/S0869813918120105