An integrated approach to the pathogenetic therapy of constipation

Author:

Burkov Sergey Gennadievich1

Affiliation:

1. Polyclinic No. 3 of the Administrative Department of the President of the Russian Federation

Abstract

The data on the causes of defecation disorders, mechanisms of normal defecation, and pathogenetic aspects of constipation are presented. Functional gastrointestinal disorders are considered as a common pathology of the gastrointestinal tract, which is based on combined morphological and physiological abnormalities associated with visceral hypersensitivity, disorders of gastrointestinal motility, protective mucous barrier, immune function and the composition of the intestinal microbiota. The article discusses the possibility of using the drinking medicinal mineral water Zajecicka Horka (Zayechitskaya bitter) for intestinal pathology and other functional gastrointestinal disorders.

Publisher

PANORAMA Publishing House

Reference12 articles.

1. Drossman DA, Hasler WL. Rome IV — Functional GI disorders: disorders of Gut-Brain interaction. Gastro enterology, 2016; 150 (6): 1262–79.

2. Baryshnikov E. N., Rumiantsev V. G. Zapory v praktike gastroenterologa [Constipation in the practice of a gastroenterologist] // Consilium medicum. — 2007. — Vol. 9. — No. 7. — P. 38–43. (In Russ.)

3. Grigorieva G. Zapory: sovremennoe sostoianie problemy [Constipation: current state of the problem] // Vrach [Doctor]. — 2010. — No. 3. — P. 52–54. (In Russ.)

4. Lazebnik L. B., Turkina S. V., Golovanova E. V., Ardatskaia M. D., Ostroumova O. D., Komissarenko I. A., Korochanskaia N. V., Kozlova I. V., Uspenskii Iu. P., Fominykh Iu. A., Levchenko S. V., Loranskaia I. D., Tkachenko E. I., Sitkin S. I., Bakulin I. G., Bakulina N. V., Shemerovskii K. A. Zapory u vzroslykh [Constipation in adults]. Eksperimentalnaia i klinicheskaia gastro enterologiia [Experimental and clinical gastroenterology]. 2020; (3):10–33. https://doi.org/10.31146/1682– 8658 ecg-175 3 10 33 (In Russ.)

5. Lazebnik L. B. et al. Klinicheskie rekomendatsii: zapory u vzroslykh [Clinical guidelines: constipation in adults] // Terapiia [Therapy]. — 2020. — Vol. 6. — No. 4. — P. 77–101. (In Russ.)

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