Algorithm for predicting the duration of congenital pneumonia therapy in term newborns

Abstract

The article analyzes the results of treatment 102 cases of congenital pneumonia in term infants in order to develop algorithms for predicting the duration of congenital pneumonia in newborns and prevent the development of adverse effects. To develop predictors of the duration of congenital pneumonia, newborns are divided into two alternative groups with a duration of treatment of less than 14 days and more than 15. The nature of anamnestic and paraclinical factors on the duration of congenital pneumonia in children and predictive properties of these factors. It was found that the duration of therapy and, as a consequence, the possible development of adverse effects in newborns are influenced by pathological factors on the part of both mother and child. Significant direct correlation between the duration of congenital pneumonia on the part of the mother was found: colpitis, low- and polyhydramnios, the presence of inflammatory diseases of the genitourinary system, acute respiratory diseases suffered by the mother during pregnancy and premature ejaculation amniotic fluid during delivery. Gestational age less than 38 weeks, slowing the growth and development of the newborn, Apgar score at the 5th minute of life less than 6 points, CRP level more than 19 mg / l and bilateral localization of pneumonia according to X-ray examination are neonatal prognostic value for the duration of treatment of congenital pneumonia. Approbation of the prediction algorithm revealed 88,9 % correct, 9,5 % — undefined and 1,6 % — erroneous results, which corresponds to the high (≥ 95 %) reliability of the algorithm and allows its use to predict the duration of the disease and the likelihood of complications of congenital pneumonia.