Effect of transcranial direct current stimulation on prospective memory in healthy individuals: A double-blind randomized sham-controlled trial

Author:

Aksu Serkan1ORCID,Özsayın Eda2ORCID,Aslan Aslı Esin2ORCID,Kaya Yusuf2ORCID,Karamursel Sacit3ORCID

Affiliation:

1. MUĞLA SITKI KOÇMAN ÜNİVERSİTESİ

2. ISTANBUL UNIVERSITY, FACULTY OF LETTERS, DEPARTMENT OF PSYCHOLOGY, PSYCHOLOGY PR.

3. KOÇ ÜNİVERSİTESİ, TIP FAKÜLTESİ, TEMEL TIP BİLİMLERİ BÖLÜMÜ, FİZYOLOJİ ANABİLİM DALI

Abstract

Aim: Prospective memory (PM) has an immense role in the activities of daily living and deficits of PM are common in various neuropsychiatric disorders. Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that yields favorable outcomes yet only a few studies concerning PM with hindering results exist. The present double-blind cross-over randomized sham-controlled study aimed to assess the effect of a single-session of left-righr/sham tDCS over the prefrontal cortex on event-related PM in healthy individuals. Materials and Methods: 24 participants were administered a single session of 2 mA 20-minute left/right anodal or sham tDCS segregated by 7 days. An event-based PM task was utilized before and after tDCS every week to evaluate PM. Results: No effects of tDCS on PM were found. Conclusion: The present results argue against the effect of a single-session of tDCS over the prefrontal cortices on event-related PM. TDCS studies adopting divergent parameters are required.

Funder

The authors declare no potential conflicts of interest. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Publisher

Adiyaman University

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