Kandungan Total Flavonoid Dari Ekstrak Metanol Akar Imperata cylindrical (L) Beauv. (Alang-alang)

Abstract

Masyarakat di Sulawesi Tenggara telah memanfaatkan akar alang-alang (Imperata cylindrica) sebagai obat hipertensi. Ekstrak methanol akar alang-alang dari Kendari terbukti mempunyai aktivitas antihipertensi. Studi menunjukkan senyawa-senyawa fenolat dapat menurunkan tekanan darah. Aktivitas penurunan tekanan darah dikarenakan senyawa-senyawa fenolat mempunyai aktivitas antioksidan dan kemampuan menghambat angiotensin converting enzyme (ACE). Berdasarkan penelitian yang dilaporkan, tujuan penelitian ini menentukan adanya flavonoid, dan mengukur kandungan flavonoid total dengan menggunakan metode aluminium klorida. Hasil analisis menunjukkan bahwa ekstrak mengandung flavonoid, dengan kandungan total flavonoid 1,17%. Berdasarkan hasil diatas, dapat disimpulkan bahwa ekstrak mengandung flavonoid, and kadar total flavonoid 1,17%.   People in Southeast Sulawesi have used alang-alang (Imperata cylindrica) root as anti-hypertension.Methanol extract of alang-alang from Kendari has been found to have anti-hypertensive activity. Previous studies reported that phenolic compounds could decrease blood pressure. The anty-hipertensive actvity might be due to anti-oxidant activity and inhibition of angiotensin converting enzyme (ACE) of those phenolic compounds.  Based on the previous studies, this research aimed to evaluate the presence of flavonoid and determine the total flavonoid content using Aluminium Chloride method.The results showed that the extract contained flavonoid with total flavonoid content was 1.17%. Based on the result, it can be concluded that the extract contained flavonoid and the total flavonoid content was 1.17%.