The state of the alveolar bone tissue depending on the vitality of the tooth pulp according to the saliva indicators of patients with moderate periodontitis

Abstract

Aim. To evaluate the results of surgical treatment of patients with moderate chronic periodontitis with different dental pulp status by determining sRANKL, OPG and FGF-2 in mixed saliva and dynamic densitotomometry data.Materials and methods. Surgical treatment of 24 patients with moderate chronic periodontitis was performed. Three months before the operation, according to the indications, endodontic treatment of the examined teeth was performed in some patients. Depending on the status of the dental pulp, the patients were divided into two groups: I – patients with vital teeth, II – patients with teeth after endodontic treatment. Before and after surgery, all patients underwent clinical examination, enzyme immunoassay of saliva remodeling markers and optical densitotomometry of periodontal bone to compare the results of treatment. Results. The OHI-S index showed a significant decrease in the mean value by 12 months of observation in both groups, which was statistically significant. Higher indices of the PI index by the end of the observation period were detected in the area of depulpated teeth. An equivalent dynamics of a decrease in the value of periodontal attachment according to the CAL index was revealed in both groups after treatment. The saliva showed an equivalent decrease in sRANKL, an increase in OPG by the end of the observation period, statistically insignificant when compared between groups. FGF-2 remained undetected at any of the observation periods in all groups. Densitotomometry data indicated an increase in the density characteristics of periodontal bone by the end of observations with a stable dependence on lower values in the area of depulpated teeth. Conclusions. In the saliva of patients, the processes of periodontal bone resorption were found to be statistically equivalent in intensity, regardless of the status of the dental pulp. The absence of FGF-2 content in saliva until the end of the observation period should be considered as an indicator of periodontal healing of vital and depulpated teeth by the formation of fibrous connective tissue. Dynamic densitotomometry of alveolar bone tissue revealed statistically significantly lower density characteristics in the area of teeth with a condition after endodontic treatment.