Analysis of bactericidal effects of sodium hypochlorite and chlorhexidine on resistantbiofilm microorganisms (E. Faecalis, C. Albicans).

Author:

Khabadze Z. S.1ORCID,Generalova Yu. A.1,Shubaeva V. S.1,Ismailov F. R.1,Sheroziia M. G.1,Nedashkovsky A. A.1,Negorelova Ya. A.1

Affiliation:

1. Medical Institute RUDN University

Abstract

Aim. To analyze current data on the bactericidal efficacy of endodontic irrigants, in particular, sodium hypochlorite and chlorhexidine in different concentrations relative to the elimination of resistant microorganisms (E. Faecalis, C. Albicans). Irrigation is an important stage in the treatment of root canals, it prevents the further contamination of the canals with microorganisms. However, irrigants do not always cope with this function, which leads to the occurrence of a secondary infection.Materials and methods. The study of publications was produced in the electronic databases such as Google Scholar, PubMed and ScienceDirect in the course of a systematic review of the literature. Included articles contain information about various types of irrigants and their antimicrobial effect.Results. 73 articles were viewed during the review. After analyzing the literature for inclusion criteria, the total number of publications has become 41.Conclusions. According to literature data, irrigation solutions in widely used by clinicians concentrations (sodium hypochlorite 3%, chlorhexidine 2%) are not able to completely eliminate E. faecalis and C. albicans from the root canal system. 

Publisher

Khabadze ZS

Reference41 articles.

1. Zargar N, Marashi MA, Ashraf H, Hakopian R, Beigi P. Identification of microorganisms in persistent/secondary endodontic infections with respect to clinical and radiographic findings: bacterial culture and molecular detection. Iran J Microbiol. 2019;11(2):120-128.

2. Maryam Pourhajibagher, Roghayeh Ghorbanzadeh, Steven Parker, Nasim Chiniforush, Abbas Bahador. The evaluation of cultivable microbiota profile in patients with secondary endodontic infection before and after photo-activated disinfection. Photodiagnosis and Photodynamic Therapy, Volume 18, 2017, Pages 198-203.

3. M. Pourhajibagher, A. Bahador. Is antimicrobial agents can considered as effective weapons against endodontic infections by Enterococcus faecalis? Der Pharma Chemica, 7 (2015), pp. 196-200.

4. M.E. tysakowska, A. Ciebiada-Adam iec, M. Sienkiewicz, J. Sokolowski, K. Banaszek. The cultivable microbiota of primary and secondary infected root canals, their susceptibility to antibiotics and association with the signs and symptoms of infection. Int. Endod. J., 49 (2016), pp. 422-430.

5. Jhajharia K, Parolia A, Shetty KV, Mehta LK. Biofilm in endodontics: A review. J Int Soc Prev Community Dent. 2015;5(1):1-12.

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