MICROSCOPIC CHANGES IN MUSCLES OF RABBITS WITH EXPERIMENTALLY DAMAGED MUSCLE TISSUE UNDER THE INFLUENCE OF TRANSPLANTED MESENCHYMAL STEM CELLS

Abstract

Due to the high level of activity of some animals, particularly sports and working animals, muscle injuries are becoming a serious and urgent problem for veterinarians. Sporting events, training and work duties can lead to tears, strains and other injuries to skeletal muscle tissue. Muscle injuries in sports and working animals are a complex problem that requires a careful and comprehensive approach to treatment. These injuries can lead to pain, restricted movement and loss of performance. Traditional treatments, while effective, are often lengthy and not always successful. Therefore, scientists and veterinarians are constantly looking for new and more effective ways to treat and rehabilitate animals to help them recover from injuries faster and more fully. The main purpose of this article is to review, summarise and analyse histological studies investigating the use of allogeneic mesenchymal stem cells in veterinary medicine for regenerative therapy. An additional goal of the article is to review the results of these studies and highlight the main conclusions regarding the potential use of MSCs in veterinary practice. The main role in cell therapy is played by allogeneic mesenchymal stem cells (MSCs). These cells, which do not have a specific differentiation, can independently renew themselves and develop into cells with specific functions, making them effective for tissue repair. It is especially important to note that mesenchymal stem cells are promising for veterinary medicine because they are easy to isolate and cultivate. The article discusses the use of allogeneic mesenchymal stem cells for tissue repair in veterinary medicine in experimental animals, taking into account the results of scientific research conducted by the authors of the article. The use of a new and promising method of treating animals with damaged muscle tissue based on cellular regeneration can significantly accelerate the recovery of animals after injury and avoid side effects that often occur with traditional treatments.