THE EFFICIENCY OF THE DRUG APPLIKUS-VET IN THE COMPLEX THERAPY OF CATS WITH CLINICAL SIGNS OF ASEPTIC SKIN NECROSIS

Abstract

In order to reduce the use of antibiotics for the treatment of skin diseases in dogs and cats it is relevant to introduce alternative drugs that have antimicrobial properties into veterinary practice. Applikus-vet is a new domestic combined veterinary agent for external use, which has adsorption and bactericidal action. The preparation is designed on the basis of hydrogel of methylcremic acid with immobilized Cuprum ions and is intended for the treatment of wounds and ulcerative lesions of the skin. Hydrogel of methylcremic acid has an adsorption capacity, Cuprum ions have an antimicrobial effect and cause the denaturation of microorganism’s proteins. The article outlines the clinical study of a new veterinary drug Applikus-vet, paste for external use, production of PJSC "EOF" Creom-Farm "(Ukraine), in the treatment of cats with clinical signs of aseptic skin necrosis (brittle skin syndrome). The drug was used in the complex treatment of two cats of long-haired breeds – female, aged 7 years, and male, 14 years of age, with clinical signs of aseptic skin necrosis in the area of the thoracic, the lumbar departments of the back and abdominal wall. The female had a much larger area of the affected skin than the male. Diagnosis was put on the basis of anamnesis, a clinical picture of the disease. The veterinarian of the clinic prescribed complex therapy, which included the drug Applikus-vet for application to the wounds of animals. The general course of treatment with the test drug lasted 4–8 weeks. The drug Applikus-vet showed good therapeutic efficiency in the complex treatment of cats with clinical signs of aseptic skin necrosis. Depending on the complexity of the disease, epithelialization and reduction of the inflammatory process in the affected area of animal’s skin were observed on 21–35 days of treatment. A significant decrease in the area of the affected skin and the formation of scars and scab was noted on 28–50 days of treatment. In this case, the drug was well tolerated by animals, didn’t show unexpected negative local and general effects. According to the results of laboratory tests, the positive effect of the drug Applikus-vet was found in the complex therapy of aseptic skin necrosis on the morpho-functional condition of the cat’s organism, which is confirmed by the normalization of most morphological and biochemical indicators of blood to the values of clinically healthy animals.