Canadian guidelines on HIV pre-exposure prophylaxis (PrEP) and non-occupational post-exposure prophylaxis (nPEP): Discussion beyond the guidelines and commentary on the role of infectious diseases specialists

Author:

Singh Ameeta E1,Tan Darrell2,Hull Mark3,Bogoch Isaac I4,MacPherson Paul5,Tremblay Cecile6,Shafran Stephen1

Affiliation:

1. Division of Infectious Diseases, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

2. Division of Infectious Diseases, St. Michael’s Hospital, Toronto, Ontario, Canada

3. Division of Infectious Diseases, University of British Columbia, Vancouver, British Columbia, Canada

4. Divisions of General Internal Medicine and Infectious Diseases, Toronto General Hospital, Toronto, Ontario, Canada

5. Division of Infectious Diseases, The Ottawa Hospital, Ottawa, Ontario, Canada

6. Centre de Recherche du Centre Hospitalier de l’Université de Montréal, Montréal, Québec, Canada

Abstract

Pre-exposure prophylaxis (PrEP) and non-occupational post-exposure prophylaxis (nPEP) are part of combination HIV prevention strategies that include behavioural interventions such as condoms and risk-reduction counselling. A 25-member panel was convened to develop Canadian guidelines for PrEP and nPEP, with the full guidelines recently published in the Canadian Medical Association Journal (CMAJ). This article provides a discussion beyond the guideline, highlighting areas of particular interest to infectious disease (ID) specialists and discusses the possible role of ID specialists as access to both PrEP and nPEP become more widely available across the country.

Publisher

University of Toronto Press Inc. (UTPress)

Subject

Infectious Diseases,Microbiology (medical)

Reference69 articles.

1. HIV in Canada—Surveillance Report, 2016

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3. Safety and Efficacy of a Dapivirine Vaginal Ring for HIV Prevention in Women

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5. 5. World Health Organization (WHO). Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection [Internet]. Geneva: WHO; 2013 Jun [cited 2018 Jan 31]. Available from: http://apps.who.int/iris/bitstream/10665/85321/1/9789241505727_eng.pdf?ua=1. June.

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