2020–2021 AMMI Canada guidance on the use of antiviral drugs for influenza in the setting of co-circulation of seasonal influenza and SARS-CoV-2 viruses in Canada

Author:

Mubareka Samira1,Aoki Fred Y2,Allen Upton D345,Hatchette Todd F67,Papenburg Jesse78,Evans Gerald A9

Affiliation:

1. Department of Laboratory Medicine and Molecular Diagnostics, Sunnybrook Health Sciences Centre, and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada

2. Medical Microbiology and Pharmacology and Therapeutics, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada

3. Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada

4. Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada

5. Division of Infectious Diseases, Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada

6. Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada

7. Department of Pathology and Laboratory Medicine, Nova Scotia Health, Halifax, Nova Scotia, Canada

8. Division of Pediatric Infectious Diseases, Department of Pediatrics, Montreal Children’s Hospital, McGill University Health Centre, Montreal, Quebec, Canada

9. Division of Microbiology, Department of Clinical Laboratory Medicine, Optilab Montreal, McGill University Health Centre, Montreal, Quebec, Canada

Abstract

We provide an update to the Association of Medical Microbiology and Infectious Disease Canada foundation guidance for the upcoming 2020–2021 influenza season in Canada. Important issues for this year include the implications of co-circulation of SARS-CoV-2, the role of diagnostic testing, and a restatement of dosing and administration recommendations for neuraminidase inhibitors in various age groups and underlying health conditions. Although peramivir and baloxivir are now licensed in Canada, neither is currently marketed, so this guidance focuses on further optimizing the use of oseltamivir and zanamivir.

Publisher

University of Toronto Press Inc. (UTPress)

Subject

Infectious Diseases,Microbiology (medical)

Reference28 articles.

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