Maternal obesity characterized by gestational diabetes increases the susceptibility of rat offspring to hepatic steatosis via a disrupted liver metabolome

Author:

Pereira Troy J.123,Fonseca Mario A.123,Campbell Kristyn E.123,Moyce Brittany L.123,Cole Laura K.123,Hatch Grant M.123,Doucette Christine A.234,Klein Julianne5,Aliani Michel6,Dolinsky Vernon W.123

Affiliation:

1. Department of Pharmacology & Therapeutics

2. Diabetes Research Envisioned and Accomplished in Manitoba (DREAM) Research Theme

3. Children's Hospital Research Institute of Manitoba

4. Department of Physiology and Pathophysiology

5. Diagnostic Services of Manitoba; Winnipeg MB Canada

6. Department of Human Nutrition; University of Manitoba; Winnipeg MB Canada

Funder

Children's Hospital Foundation of Manitoba

Children's Hospital Research Institute of Manitoba (CHF/CHRIM)

Manitoba Medical Services Foundation (MMSF)

Canadian Institutes of Health Research (CIHR)

Publisher

Wiley

Subject

Physiology

Reference49 articles.

1. Oxidative stress and altered lipid homeostasis in the programming of offspring fatty liver by maternal obesity;Alfaradhi;Am J Physiol Regul Integr Comp Physiol,2014

2. Death rates from stroke in England and Wales predicted from past maternal mortality;Barker;Br Med J (Clin Res Ed),1987

3. Colorimetric assay methods for free and phosphorylated glyceric acids;Bartlett;J Biol Chem,1959

4. Altered adipose tissue metabolism in offspring of dietary obese rat dams;Benkalfat;Clin Sci (Lond),2011

5. Time course of changes in serum oxidant/antioxidant status in overfed obese rats and their offspring;Bouanane;Clin Sci (Lond),2009

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