Myths and methodologies: Cardiopulmonary exercise testing for surgical risk stratification in patients with an abdominal aortic aneurysm; balancing risk over benefit

Author:

Bailey Damian M.1ORCID,Davies Richard G.12,Rose George A.1ORCID,Lewis Michael H.1,Aldayem Ahmed Abd3,Twine Chistopher P.4,Awad Wael15,Jubouri Matti6,Mohammed Idhrees7,Mestres Carlos A.8,Chen Edward P.9,Coselli Joseph S.101112,Williams Ian M.13,Bashir Mohamad113,

Affiliation:

1. Neurovascular Research Laboratory, Faculty of Life Sciences and Education University of South Wales Glamorgan UK

2. Department of Anaesthetics University Hospital of Wales Cardiff UK

3. Department of Vascular Surgery University Hospital of Wales Cardiff UK

4. Department of Surgery University of Bristol Bristol UK

5. Department of Cardiothoracic Surgery Bart's Heart Centre, St Bartholomew's Hospital, Bart's Health NHS Trust London UK

6. Hull York Medical School University of York York UK

7. Institute of Cardiac and Aortic Disorders SRM Institutes for Medical Science (SIMS Hospital) Chennai Tamil Nadu India

8. Department of Cardiac Surgery University Hospital Zürich Zürich Switzerland

9. Division of Cardiovascular and Thoracic Surgery Duke University Medical Center Durham North Carolina USA

10. Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery Baylor College of Medicine Houston Texas USA

11. The Texas Heart Institute Houston Texas USA

12. St Luke's‐Baylor St. Luke's Medical Center Houston Texas USA

13. Vascular and Endovascular Surgery Health & Education Improvement Wales Cardiff UK

Abstract

AbstractThe extent to which patients with an abdominal aortic aneurysm (AAA) should exercise remains unclear, given theoretical concerns over the perceived risk of blood pressure‐induced rupture, which is often catastrophic. This is especially pertinent during cardiopulmonary exercise testing, when patients are required to perform incremental exercise to symptom‐limited exhaustion for the determination of cardiorespiratory fitness. This multimodal metric is being used increasingly as a complementary diagnostic tool to inform risk stratification and subsequent management of patients undergoing AAA surgery. In this review, we bring together a multidisciplinary group of physiologists, exercise scientists, anaesthetists, radiologists and surgeons to challenge the enduring ‘myth’ that AAA patients should be fearful of and avoid rigorous exercise. On the contrary, by appraising fundamental vascular mechanobiological forces associated with exercise, in conjunction with ‘methodological’ recommendations for risk mitigation specific to this patient population, we highlight that the benefits conferred by cardiopulmonary exercise testing and exercise training across the continuum of intensity far outweigh the short‐term risks posed by potential AAA rupture.

Publisher

Wiley

Subject

Physiology,Physiology (medical),Nutrition and Dietetics,Physiology,Physiology (medical),Nutrition and Dietetics

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